Metabosol

•           Healthy Blood Sugar and Insulin Levels:

•           Lipid Metabolism

•           Appetite-suppressant

•           Pancreatic, Kidney, and Gastro- Intestinal Health

•           Antihyperlipidemic

Metabosol is a proprietary blend of herbal and mineral formula designed as a nutritional dietary supplement for individuals who are concerned with maintaining healthy levels of insulin, glucose, lipid levels, and weight. This premium metabolic compound includes Gymnema Sylvestre, Berberine, Salvia Miltiorrhiza, Bamboo Salt, Zeolite, and Alpha-Lipoic Acid designed to help maintain healthy glucose levels while boosting metabolic functions.

FUNCTIONS:

Gymnema Sylvestre: This shrub that is native to tropical forests of India has been used for hundreds of years as traditional herbal medicine used to treat and control diabetes. There have been many recent studies showing the effectiveness of the plant in terms of protecting pancreatic beta-cells from cytokine-induced apoptosis, as well as lowering serum Triacyl.¹ They have indicated a dramatic reduction in blood glucose in diabetes patients and were effective in controlling hyperglycemia in type 2 diabetic patients.² It is hypothesized that Gymnema Sylvestre works by sharing a molecular structure similar to glucose, allowing it to fill the receptor location on taste buds, reducing sugar cravings.³ Additionally, it has also shown to decreases the absorption of sugar from the intestine, which has proven useful both against diabetic patients and against obesity.⁴ This is certainly an interesting plant with abilities to help fight sugar cravings, lower high blood sugar levels, and lower inflammation.

Berberine: Berberine is a yellow alkaloid found in numerous plants including, goldenseal, goldthread, Oregon grape, and tree turmeric. This active component has been used to treat diabetes for thousands of years. In fact, in China, Berberine is currently being used as an OTC drug that is used to treat gastrointestinal (GI) tract infections.⁵ It has been widely studied and has shown significant medical potential. Berberine has a hypoglycemic effect that is comparable to metformin where patients taking berberine showed significant decreases to fasting blood glucose, plasma triglycerides, and postprandial blood glucose.⁶ In another study examining the mechanism of action, study subjects given berberine were shown to have increased insulin sensitivity and enhanced glucose metabolism.⁷ The herb can improve the body’s ability to absorb sugar, reducing blood sugar levels, and most importantly normalize blood sugar levels.

Salvia Miltiorrhiza: This plant is also known as red sage or Danshen (Chinese name) and is highly prized as an herb that has been used clinically for thousands of years. Danshen has been described and used by many Traditional Chinese Medicine (TCM) practitioners to treat cardiovascular diseases (CVD). Clinically, Danshen has been most effective for clinical patients with hypertension and coronary artery disease.⁸ Showing marked improvements in both lab tested and observed values. The plant contains compounds that improve microcirculation, causing blood vessels to dilate, while suppressing platelet adhesion and aggregation.

Bamboo Salt originates from Korea and is made by putting sea salt in bamboo trunks. These trunks are then roasted, and the minerals from the bamboo and clay are infused into the sea salt. This salt is very potent for its anti-inflammatory properties and has shown greater anti-metastatic effect on cancer cells than other salts.⁹ What makes Bamboo Salt so effective is that the salt contains more than 70 different kinds of minerals due how it is prepared, including essential minerals such as calcium, phosphorous, magnesium, iron, zinc, sulfur, and many others.¹⁰ This allows the salt to resupply any missing minerals from the human body and provides beneficial effects at the cellular level like supporting healthy metabolic activity, cell proliferation, and protein synthesis.

Zeolite: Zeolite are porous structures that often form negatively charged channels occupied by positively charged alkali, alkali earth, and divalent ions. The final Si/Al ratio in a zeolite determines the attraction of cations and the amount of charge accumulated.¹¹ This ability for ion attraction causes naturally occurring zeolites to be used as drying agents, used as detergents, and in water and air purifiers. The porous structure of a naturally formed zeolite is often filled with ions such as sodium, potassium, magnesium, calcium, and barium.

Alpha-Lipoic Acid: Alpha-Lipoic Acid (ALA) is a naturally occurring short-chain fatty acid that is marketed as an OTC nutritional antioxidant support. This compound has been widely studied and has shown effectiveness in clinical trials in treating symptomatic diabetic polyneuropathy.^12–15 This fatty acid not only improved neuropathic symptoms and corrected neuropathic deficits at a clinically meaningful degree, but was also shown to be safe. Additionally, there have been other studies conducted studying ALA’s effectiveness as an anti-obesity supplementation. In a randomized double-blind placebo controlled trial with 360 individuals, researchers found that the group supplementing with ALA lost significantly more weight.¹⁶ ALA seems to have a wide range of effects leading to the weight loss including, decreasing food intake, enhancing energy expenditure, and improving mitochondrial function.

SUGGESTED USE

Adults take 1-2 capsules. Three times daily after meals or as directed by a healthcare professional.

INGREDIENTS

This premium metabolic compound includes Gymnema Sylvestre, Berberine, Salvia Miltiorrhiza, Bamboo Salt, Zeolite, and Alpha-Lipoic Acid

SIDE EFFECTS

No adverse side effects reported.

STORAGE

Store in a cool, dry place, away from direct light. Keep out of reach of children.

References

1.          Al-Romaiyan A, Liu B, Persaud S, Jones P. A novel Gymnema sylvestre extract protects pancreatic beta-cells from cytokine-induced apoptosis. Phyther Res. 2019.

2.          Baskaran K, Ahamath BK, Shanmugasundaram KR, Shanmugasundaram ERB. Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol. 1990.

3.          Sahu NP, Mahato SB, Sarkar SK, Poddar G. Triterpenoid saponins from Gymnema Sylvestre. Phytochemistry. 1996.

4.          Kanetkar P, Singhal R, Kamat M. Serial Review Gymnema Sylvestre: A Memoir. Vol 41.; 2007.

5.          Ni YX. Therapeutic effect of berberine on 60 patients with type II diabetes mellitus and experimental research. Zhong Xi Yi Jie He Za Zhi. 1988.

6.          Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008.

7.          Yin J, Gao Z, Liu D, Liu Z, Ye J. Berberine improves glucose metabolism through induction of glycolysis. Am J Physiol - Endocrinol Metab. 2008.

8.          Gao ZY, Xu H, Shi DZ, Wen C, Liu BY. Analysis on outcome of 5284 patients with coronary artery disease: The role of integrative medicine. J Ethnopharmacol. 2012.

9.          Yi R, Qi YC, Zhao X, Park KY. Anti-tumor activities of bamboo salt on sarcoma 180 tumor-bearing BALB/c mice. Biomed Res. 2017.

10.        Hwang IM, Yang JS, Kim SH, et al. Elemental Analysis of Sea, Rock, and Bamboo Salts by Inductively Coupled Plasma-Optical Emission and Mass Spectrometry. Anal Lett. 2016.

11.        Canli M, Abali Y, Bayca SU. Removal of methylene blue by natural and ca and k-exchanged zeolite treated with hydrogen peroxide. Physicochem Probl Miner Process. 2013.

12.        Ziegler D, Nowak H, Kempler P, Vargha P, Low PA. Treatment of symptomatic diabetic polyneuropathy with the antioxidant α-lipoic acid: A meta-analysis. Diabet Med. 2004.

13.        Ametov AS, Barinov A, Dyck PJ, et al. The sensory symptoms of diabetic polyneuropathy are improved with α-lipoic acid: The Sydney trial. Diabetes Care. 2003.

14.        Ziegler D, Ametov A, Barinov A, et al. Oral treatment with α-lipoic acid improves symptomatic diabetic polyneuropathy. Diabetes Care. 2006.

15.        Gu XM, Zhang SS, Wu JC, et al. Efficacy and safety of high-dose α-lipoic acid in the treatment of diabetic polyneuropathy. Natl Med J China. 2010.

16.        Koh EH, Lee WJ, Lee SA, et al. Effects of alpha-lipoic acid on body weight in obese subjects. Am J Med. 2011.